The most crucial challenges for UAVs are planning paths and avoiding obstacles in their way. In recent years, a wide variety of path-planning algorithms have been developed. These algorithms have successfully solved path-planning problems; however, they suffer from multiple challenges and limitations. To test the effectiveness and efficiency of three widely used algorithms, namely A*, RRT*, and Particle Swarm Optimization (PSO), this paper conducts extensive experiments in 3D urban city environments cluttered with obstacles. Three experiments were designed with two scenarios each to test the aforementioned algorithms. These experiments consider different city map sizes, different altitudes, and varying obstacle densities and sizes in the environment. According to the experimental results, the A* algorithm outperforms the others in both computation efficiency and path quality. PSO is especially suitable for tight turns and dense environments, and RRT* offers a balance and works well across all experiments due to its randomized approach to finding solutions.

Efficient and safe navigation of Unmanned Aerial Vehicles (UAVs) is critical for various applications, including combat support, package delivery and Search and Rescue Operations. This paper introduces the Tangent Intersection Guidance (TIG) algorithm, an advanced approach for UAV path planning in both static and dynamic environments. The algorithm uses the elliptic tangent intersection method to generate feasible paths. It generates two sub-paths for each threat, selects the optimal route based on a heuristic rule, and iteratively refines the path until the target is reached. Considering the UAV kinematic and dynamic constraints, a modified smoothing technique based on quadratic Bézier curves is adopted to generate a smooth and efficient route. Experimental results show that the TIG algorithm can generate the shortest path in less time, starting from 0.01 seconds, with fewer turning angles compared to A*, PRM, RRT*, Tangent Graph, and Static APPATT algorithms in static environments. Furthermore, in completely unknown and partially known environments, TIG demonstrates efficient real-time path planning capabilities for collision avoidance, outperforming APF and Dynamic APPATT algorithms.

The prediction of amyloidogenicity in peptides and proteins remains a focal point of ongoing bioinformatics. The crucial step in this field is to apply advanced computational methodologies. Many recent approaches to predicting amyloidogenicity within proteins are highly based on evolutionary motifs and the individual properties of amino acids. It is becoming increasingly evident that the sequence information-based features show high predictive performance. Consequently, our study evaluated the contextual features of protein sequences obtained from a pretrained protein large language model leveraging bidirectional LSTM and GRU to predict amyloidogenic regions in peptide and protein sequences. Our method achieved an accuracy of 84.5% on 10-fold cross-validation and an accuracy of 83% in the test dataset. Our results demonstrate competitive performance, highlighting the potential of LLMs in enhancing the accuracy of amyloid prediction.

Artificial intelligence (AI) developers are increasingly building language models with warm and empathetic personas that millions of people now use for advice, therapy, and companionship. Here, we show how this creates a significant trade-off: optimizing language models for warmth undermines their reliability, especially when users express vulnerability. We conducted controlled experiments on five language models of varying sizes and architectures, training them to produce warmer, more empathetic responses, then evaluating them on safety-critical tasks. Warm models showed substantially higher error rates (+10 to +30 percentage points) than their original counterparts, promoting conspiracy theories, providing incorrect factual information, and offering problematic medical advice. They were also significantly more likely to validate incorrect user beliefs, particularly when user messages expressed sadness. Importantly, these effects were consistent across different model architectures, and occurred despite preserved performance on standard benchmarks, revealing systematic risks that current evaluation practices may fail to detect. As human-like AI systems are deployed at an unprecedented scale, our findings indicate a need to rethink how we develop and oversee these systems that are reshaping human relationships and social interaction.

--Recent years have witnessed remarkable progress in developing Vision-Language Models (VLMs) capable of processing both textual and visual inputs. These models have demonstrated impressive performance, leading to their widespread adoption in various applications. However, this widespread raises serious concerns regarding user privacy, particularly when models inadvertently process or expose private visual information. We propose a novel attack strategy that selectively conceals information within designated Region Of Interests (ROIs) in an image, effectively preventing VLMs from accessing sensitive content while preserving the semantic integrity of the remaining image. Unlike conventional adversarial attacks that often disrupt the entire image, our method maintains high coherence in unmasked areas. Experimental results across three state-of-the-art VLMs namely LLaV A, Instruct-BLIP, and BLIP2-T5 demonstrate up to 98% reduction in detecting targeted ROIs, while maintaining global image semantics intact, as confirmed by high similarity scores between clean and adversarial outputs. We believe that this work contributes to a more privacy-conscious use of multimodal models and offers a practical tool for further research, with the source code publicly available at https://github.com/hbrachemi/Vlm Vision-Language Models (VLMs) have emerged as a powerful paradigm in artificial intelligence, seamlessly integrating visual and textual information to achieve remarkable performance in various tasks such as image captioning, visual question answering, and document understanding [1]-[5]. This led to their rapid adoption in numerous applications, including content creation, customer service, and information retrieval. However, the widespread use of VLMs raises critical concerns regarding the privacy and security of user data.

This short paper gives an overview of the XCSP3 solver implemented in Picat. Picat provides several constraint modules, and the Picat XCSP3 solver uses the sat module. The XCSP3 solver mainly consists of a parser implemented in Picat, which converts constraints from XCSP3 format to Picat. The solver demonstrates the strengths of Picat, a logic-based language, in parsing, modeling, and encoding constraints into SAT. The high performance of the solver in recent XCSP competitions demonstrates the viability of using a SAT solver to solve general constraint satisfaction and optimization problems.

In material physics, characterization techniques are foremost crucial for obtaining the materials data regarding the physical properties as well as structural, electronics, magnetic, optic, dielectric, and spectroscopic characteristics. However, for many materials, ensuring availability and safe accessibility is not always easy and fully warranted. Moreover, the use of modeling and simulation techniques need a lot of theoretical knowledge, in addition of being associated to costly computation time and a great complexity deal. Thus, analyzing materials with different techniques for multiple samples simultaneously, still be very challenging for engineers and researchers. It is worth noting that although of being very risky, X-ray diffraction is the well known and widely used characterization technique which gathers data from structural properties of crystalline 1d, 2d or 3d materials. We propose in this paper, a Smart GRU for Gated Recurrent Unit model to forcast structural characteristics or properties of thin films of tin oxide SnO$_2$(110). Indeed, thin films samples are elaborated and managed experimentally and the collected data dictionary is then used to generate an AI -- Artificial Intelligence -- GRU model for the thin films of tin oxide SnO$_2$(110) structural property characterization.

With the advancements of Artifical Intelligence (AI) and Natural Language Processing (NLP) in the past decades, especially the rising of Large Language Model (LLM) and multimodality learning, softwrare engineering fields welcome AI techniques to be employed to every aspects of software cycles. Meanwhile, the research of intelligent applications has continuously been a hotspot (Zhao et al., 2021) because of the increasing amount of data of multimodalities generated in various domains. This type of software is designed to adapt to constantly changing scenarios of rich context (Zhao et al., 2021; Yue and Smith, 2021), and some examples are listed in part C of figure 1. One primary characteristic of those applications is that a great portion of their system behaviors is learned from continuous interaction with the users and environment involving detection and analysis of states and activities (Tzafestas, 2012; Yang and Newman, 2013; Cassavia et al., 2017), unlike applications of banking or insurance with more matured and stable business logic. The rapid evolution of hardware and software wheels bring more capabilities to intelligent applications meanwhile making the creation and maintenance of that software more intricate (Chu et al., 2021; Zheng et al., 2023), both fields of software engineering and intelligent applications are eager for breakthroughs in higher-level automation (HLA) - collaboratively resolving the challenges by benefiting from AI techniques.

Adverse drug reactions considerably impact patient outcomes and healthcare costs in cancer therapy. Using artificial intelligence to predict adverse drug reactions in real time could revolutionize oncology treatment. This study aims to assess the performance of artificial intelligence models in predicting adverse drug reactions in patients with cancer. This is the first systematic review and meta-analysis. Scopus, PubMed, IEEE Xplore, and ACM Digital Library databases were searched for studies in English, French, and Arabic from January 1, 2018, to August 20, 2023. The inclusion criteria were: (1) peer-reviewed research articles; (2) use of artificial intelligence algorithms (machine learning, deep learning, knowledge graphs); (3) study aimed to predict adverse drug reactions (cardiotoxicity, neutropenia, nephrotoxicity, hepatotoxicity); (4) study was on cancer patients. The data were extracted and evaluated by three reviewers for study quality. Of the 332 screened articles, 17 studies (5%) involving 93,248 oncology patients from 17 countries were included in the systematic review, of which ten studies synthesized the meta-analysis. A random-effects model was created to pool the sensitivity, specificity, and AUC of the included studies. The pooled results were 0.82 (95% CI:0.69, 0.9), 0.84 (95% CI:0.75, 0.9), and 0.83 (95% CI:0.77, 0.87) for sensitivity, specificity, and AUC, respectively, of ADR predictive models. Biomarkers proved their effectiveness in predicting ADRs, yet they were adopted by only half of the reviewed studies. The use of AI in cancer treatment shows great potential, with models demonstrating high specificity and sensitivity in predicting ADRs. However, standardized research and multicenter studies are needed to improve the quality of evidence. AI can enhance cancer patient care by bridging the gap between data-driven insights and clinical expertise.

This short paper gives an overview of the XCSP3 solver implemented in Picat. Picat provides several constraint modules, and the Picat XCSP3 solver uses the sat module. The XCSP3 solver mainly consists of a parser implemented in Picat, which converts constraints from XCSP3 format to Picat. The solver demonstrates the strengths of Picat, a logic-based language, in parsing, modeling, and encoding constraints into SAT. The solver submitted to the 2022 XCSP competition is based on the one that won the 2019 XCSP competition.